UniProt Q96BH1
E3 ubiquitin-protein ligase RNF25 (Q96BH1)
E3 ubiquitin-protein ligase RNF25 (UniProt Q96BH1), EC 6.3.2.-: 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q96BH1
- Protein
- E3 ubiquitin-protein ligase RNF25
- EC
- 6.3.2.-
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
11 records of Q96BH1 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DAY | Solution structure of the RWD domain of human ring finger protein 25 | solution nmr | A | — | — |
| 2DAY | Solution structure of the rwd domain of human ring finger protein 25 | solution nmr | A | — | — |
| 2DMF | An extended conformation of the RWD domain of human Ring finger protein 25 | solution nmr | A | — | — |
| 2DMF | An extended conformation of the rwd domain of human ring finger protein 25 | solution nmr | A | — | — |
| 5D1K | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 | x-ray diffraction | B | ZN | 3 (best 0.55) |
| 5D1K | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 | x-ray diffraction | B | — | — |
| 5D1L | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (Y165A) | x-ray diffraction | B | ZN | — |
| 5D1L | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (Y165A) | x-ray diffraction | B | — | — |
| 5D1M | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (P199A) | x-ray diffraction | B | ZN | — |
| 5D1M | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (P199A) | x-ray diffraction | B | — | — |
| Q96BH1 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF25 (Q96BH1) | predicted | A | — | 3 (best 0.46) |
Ligands
- ZN · Zinc ion · in 3 records
Experiment against prediction
- 5D1M chain B against the predicted model Q96BH1: TM-score 0.85, RMSD 1.88 Å
- 5D1M chain B against the predicted model Q96BH1: TM-score 0.85, RMSD 1.88 Å
- 5D1K chain B against the predicted model Q96BH1: TM-score 0.85, RMSD 1.91 Å
- 5D1K chain B against the predicted model Q96BH1: TM-score 0.85, RMSD 1.91 Å
- 5D1L chain B against the predicted model Q96BH1: TM-score 0.84, RMSD 1.98 Å
- 5D1L chain B against the predicted model Q96BH1: TM-score 0.84, RMSD 1.98 Å
- 2DMF chain A against the predicted model Q96BH1: TM-score 0.82, RMSD 2.42 Å
- 2DMF chain A against the predicted model Q96BH1: TM-score 0.82, RMSD 2.42 Å
- 2DAY chain A against the predicted model Q96BH1: TM-score 0.80, RMSD 2.39 Å
- 2DAY chain A against the predicted model Q96BH1: TM-score 0.80, RMSD 2.39 Å
Elsewhere
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