MolNFT v1 · #370523 · protein
AlphaFold monomer V2.0 prediction for 60S ribosomal protein L37-a (P49166)
P49166: “AlphaFold monomer V2.0 prediction for 60S ribosomal protein L37-a (P49166)”. 1 pocket (best druggability 0.28). MolNFT v1 #370523 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49166
- Type
- protein
- Length
- 88 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- 60S ribosomal protein L37-a
- UniProt
- P49166
- Pockets
- 1 · best druggability 0.28
Structure
1 distinct chain · 20% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 60S ribosomal protein L37-a | protein | 88 | 20% helix, 10% strand | P49166 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.28 | 0.75 | 12 | empty |
Compared structures
- 8PFR · Mouse RPL39L integrated into the yeast 60S ribosomal subunit · an experimental structure of the same protein · chain A against RJ, TM-score 0.94
- 5LYB · Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound… · an experimental structure of the same protein · chain A against o7, TM-score 0.94
- 5TGA · Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound… · an experimental structure of the same protein · chain A against o7, TM-score 0.93
- 5DGF · Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a… · an experimental structure of the same protein · chain A against o7, TM-score 0.93
- 8P8M · Yeast 60S ribosomal subunit, RPL39 deletion · an experimental structure of the same protein · chain A against RJ, TM-score 0.93
- 7OH3 · Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae · an experimental structure of the same protein · chain A against j, TM-score 0.93
- 7AZY · Context-specific inhibition of eukaryotic translation by macrolide antibiotics · an experimental structure of the same protein · chain A against g, TM-score 0.93
- 3JCT · Cryo-em structure of eukaryotic pre-60S ribosomal subunits · an experimental structure of the same protein · chain A against j, TM-score 0.93
- 5H4P · Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1… · an experimental structure of the same protein · chain A against j, TM-score 0.93
- 4V8Y · Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation… · an experimental structure of the same protein · chain A against Bj, TM-score 0.93
- 4V8Z · Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation… · an experimental structure of the same protein · chain A against Bj, TM-score 0.93
- 4V8T · Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 · an experimental structure of the same protein · chain A against j, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49166
- Elsewhere: UniProt P49166 · AlphaFold DB P49166
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