MolNFT v1 · #346221 · protein
AlphaFold monomer V2.0 prediction for ribonucleoside-diphosphate reductase subunit M2 (P31350)
P31350: “AlphaFold monomer V2.0 prediction for ribonucleoside-diphosphate reductase subunit M2 (P31350)”. 3 pockets (best druggability 0.67). MolNFT v1 #346221 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31350
- Type
- protein
- Length
- 389 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Ribonucleoside-diphosphate reductase subunit M2
- UniProt
- P31350
- Pockets
- 3 · best druggability 0.67
Structure
1 distinct chain · 59% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonucleoside-diphosphate reductase subunit M2 | protein | 389 | 59% helix, 0% strand | P31350 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 544 | 0.67 | 0.77 | 53 | empty |
| 2 | 473 | 0.61 | 0.75 | 33 | empty |
| 3 | 162 | 0.43 | 0.74 | 23 | empty |
Compared structures
- 3VPN · Crystal structure of human ribonucleotide reductase subunit M2 (HRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3VPN · Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3VPO · Crystal structure of human ribonucleotide reductase subunit M2 (HRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3VPO · Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3OLJ · Crystal structure of human ribonucleotide reductase subunit M2 (HRRM2) · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3OLJ · Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3VPM · Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 3VPM · Crystal structure of human ribonucleotide reductase subunit M2 (HRRM2) mutant · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 2UW2 · Crystal structure of human ribonucleotide reductase subunit R2 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 2UW2 · Crystal structure of human ribonucleotide reductase subunit R2 · an experimental structure of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31350
- Elsewhere: UniProt P31350 · AlphaFold DB P31350
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