MolNFT v1 · #339204 · protein
AlphaFold monomer V2.0 prediction for regulator of nonsense transcripts 1 (Q92900)
Q92900: “AlphaFold monomer V2.0 prediction for regulator of nonsense transcripts 1 (Q92900)”. 10 pockets (best druggability 0.84). MolNFT v1 #339204 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q92900
- Type
- protein
- Length
- 1,129 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Regulator of nonsense transcripts 1
- UniProt
- Q92900
- Pockets
- 10 · best druggability 0.84
Structure
1 distinct chain · 25% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of nonsense transcripts 1 | protein | 1129 | 25% helix, 13% strand | Q92900 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 468 | 0.84 | 0.91 | 70 | empty |
| 2 | 440 | 0.81 | 0.89 | 54 | empty |
| 3 | 343 | 0.74 | 0.86 | 41 | empty |
| 4 | 235 | 0.58 | 0.80 | 35 | empty |
| 5 | 377 | 0.57 | 0.75 | 38 | empty |
Compared structures
- 2WJY · Crystal structure of the complex between human nonsense mediated decay factors UPF1 and… · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 2WJY · Crystal structure of the complex between human nonsense mediated decay factors UPF1 and… · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 2XZP · Upf1 helicase · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2XZP · UPF1 helicase · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2WJV · Crystal structure of the complex between human nonsense mediated decay factors UPF1 and… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2WJV · Crystal structure of the complex between human nonsense mediated decay factors UPF1 and… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2GJK · Structural and functional insights into the human Upf1 helicase core · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 2GJK · Structural and functional insights into the human UPF1 helicase core · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 2GK6 · Structural and Functional insights into the human Upf1 helicase core · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 2GK6 · Structural and functional insights into the human UPF1 helicase core · an experimental structure of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92900
- Elsewhere: UniProt Q92900 · AlphaFold DB Q92900
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