MolNFT v1 · #318273 · protein
AlphaFold monomer V2.0 prediction for polypyrimidine tract-binding protein 1 (P26599)
P26599: “AlphaFold monomer V2.0 prediction for polypyrimidine tract-binding protein 1 (P26599)”. 4 pockets (best druggability 0.54). MolNFT v1 #318273 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P26599
- Type
- protein
- Length
- 531 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x34a2a32567dD00A08b524564Bc44Da034F3a2cEe
- Molecule
- Polypyrimidine tract-binding protein 1
- UniProt
- P26599
- Pockets
- 4 · best druggability 0.54
Structure
1 distinct chain · 20% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polypyrimidine tract-binding protein 1 | protein | 531 | 20% helix, 22% strand | P26599 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.54 | 0.75 | 33 | empty |
| 2 | 229 | 0.48 | 0.74 | 28 | empty |
| 3 | 101 | 0.47 | 0.80 | 20 | empty |
| 4 | 94 | 0.41 | 0.77 | 18 | empty |
Compared structures
- 2EVZ · Structure of RNA binding domains 3 and 4 of polypyrimidine tract binding protein · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 2EVZ · Structure of RNA Binding Domains 3 and 4 of Polypyrimidine Tract Binding Protein · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 2ADC · Solution structure of polypyrimidine tract binding protein RBD34 complexed with cucucu RNA · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 2ADC · Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 1QM9 · NMR, representative structure · an experimental structure of the same protein · chain A against A, TM-score 0.22
- 1QM9 · NMR, representative structure · an experimental structure of the same protein · chain A against A, TM-score 0.22
- 3ZZY · Crystal structure of a Raver1 PRI3 peptide in complex with polypyrimidine tract binding… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 3ZZY · Crystal structure of a RAVER1 PRI3 peptide in complex with polypyrimidine tract binding… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2N3O · Structure of ptb RRM1(41-163) bound to an RNA stemloop containing a structured loop… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2N3O · Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 3ZZZ · Crystal structure of a Raver1 PRI4 peptide in complex with polypyrimidine tract binding… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 3ZZZ · Crystal structure of a RAVER1 PRI4 peptide in complex with polypyrimidine tract binding… · an experimental structure of the same protein · chain A against A, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26599
- Elsewhere: UniProt P26599 · AlphaFold DB P26599
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