UniProt P26599
Polypyrimidine tract-binding protein 1 (P26599)
Polypyrimidine tract-binding protein 1 (UniProt P26599): 20 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P26599
- Protein
- Polypyrimidine tract-binding protein 1
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
21 records of P26599 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QM9 | NMR, representative structure | solution nmr | A | — | — |
| 1QM9 | NMR, representative structure | solution nmr | A | — | — |
| 1SJQ | NMR Structure of RRM1 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) | solution nmr | A | — | — |
| 1SJQ | NMR structure of RRM1 from human polypyrimidine tract binding protein isoform 1 (PTB1) | solution nmr | A | — | — |
| 1SJR | NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) | solution nmr | A | — | — |
| 1SJR | NMR structure of RRM2 from human polypyrimidine tract binding protein isoform 1 (PTB1) | solution nmr | A | — | — |
| 2AD9 | Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA | solution nmr | A | — | — |
| 2AD9 | Solution structure of polypyrimidine tract binding protein RBD1 complexed with cucucu RNA | solution nmr | A | — | — |
| 2ADB | Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA | solution nmr | A | — | — |
| 2ADB | Solution structure of polypyrimidine tract binding protein RBD2 complexed with cucucu RNA | solution nmr | A | — | — |
| 2ADC | Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA | solution nmr | A | — | — |
| 2ADC | Solution structure of polypyrimidine tract binding protein RBD34 complexed with cucucu RNA | solution nmr | A | — | — |
| 2EVZ | Structure of RNA Binding Domains 3 and 4 of Polypyrimidine Tract Binding Protein | solution nmr | A | — | — |
| 2EVZ | Structure of RNA binding domains 3 and 4 of polypyrimidine tract binding protein | solution nmr | A | — | — |
| 2N3O | Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from… | solution nmr | A | — | — |
| 2N3O | Structure of ptb RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from… | solution nmr | A | — | — |
| 3ZZY | Crystal structure of a Raver1 PRI3 peptide in complex with polypyrimidine tract binding protein RRM2 | x-ray diffraction | A, B | — | — |
| 3ZZY | Crystal structure of a RAVER1 PRI3 peptide in complex with polypyrimidine tract binding protein RRM2 | x-ray diffraction | A, B | — | — |
| 3ZZZ | Crystal structure of a Raver1 PRI4 peptide in complex with polypyrimidine tract binding protein RRM2 | x-ray diffraction | A, B | — | — |
| 3ZZZ | Crystal structure of a RAVER1 PRI4 peptide in complex with polypyrimidine tract binding protein RRM2 | x-ray diffraction | A, B | — | — |
| P26599 | AlphaFold monomer V2.0 prediction for polypyrimidine tract-binding protein 1 (P26599) | predicted | A | — | 4 (best 0.54) |
Experiment against prediction
- 3ZZZ chain A against the predicted model P26599: TM-score 0.98, RMSD 0.77 Å
- 3ZZZ chain A against the predicted model P26599: TM-score 0.98, RMSD 0.77 Å
- 3ZZY chain B against the predicted model P26599: TM-score 0.98, RMSD 0.59 Å
- 3ZZY chain B against the predicted model P26599: TM-score 0.98, RMSD 0.59 Å
- 3ZZY chain A against the predicted model P26599: TM-score 0.97, RMSD 1.06 Å
- 3ZZY chain A against the predicted model P26599: TM-score 0.97, RMSD 1.06 Å
- 1SJR chain A against the predicted model P26599: TM-score 0.89, RMSD 1.87 Å
- 1SJR chain A against the predicted model P26599: TM-score 0.89, RMSD 1.87 Å
- 2EVZ chain A against the predicted model P26599: TM-score 0.84, RMSD 2.80 Å
- 2EVZ chain A against the predicted model P26599: TM-score 0.84, RMSD 2.80 Å
Elsewhere
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