MolNFT v1 · #312107 · protein
AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-3 (P18422)
P18422: “AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-3 (P18422)”. 3 pockets (best druggability 0.45). MolNFT v1 #312107 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P18422
- Type
- protein
- Length
- 255 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa275367010E4cf621562A79b70DfF95f747bf221
- Molecule
- Proteasome subunit alpha type-3
- UniProt
- P18422
- Pockets
- 3 · best druggability 0.45
Structure
1 distinct chain · 38% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteasome subunit alpha type-3 | protein | 255 | 38% helix, 24% strand | P18422 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.45 | 0.76 | 20 | empty |
| 2 | 112 | 0.42 | 0.77 | 23 | empty |
| 3 | 53 | 0.32 | 0.78 | 20 | empty |
Compared structures
- 6TU3 · Rat 20S proteasome · an experimental structure of the same protein · chain A against G, TM-score 0.92
- 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against G, TM-score 0.91
- 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
- 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
- 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
- 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
- 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against G, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18422
- Elsewhere: UniProt P18422 · AlphaFold DB P18422
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