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AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-3 (P18422)

Analyse AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-3 (P18422) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P18422
Type
protein
Length
255 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xa275367010E4cf621562A79b70DfF95f747bf221
Molecule
Proteasome subunit alpha type-3
UniProt
P18422
Pockets
3 · best druggability 0.45

Structure

1 distinct chain · 38% helix, 24% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProteasome subunit alpha type-3protein25538% helix, 24% strandP18422

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11410.450.7620empty
21120.420.7723empty
3530.320.7820empty

Compared structures

  • 6TU3 · Rat 20S proteasome · an experimental structure of the same protein · chain A against G, TM-score 0.92
  • 6TU3 · Rat 20S proteasome · an experimental structure of the same protein · chain A against G, TM-score 0.92
  • 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against G, TM-score 0.91
  • 6EPF · Ground state 26S proteasome (GS1) · an experimental structure of the same protein · chain A against G, TM-score 0.91
  • 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
  • 6EPE · Substrate processing state 26S proteasome (SPS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
  • 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
  • 6EPC · Ground state 26S proteasome (GS2) · an experimental structure of the same protein · chain A against G, TM-score 0.89
  • 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against G, TM-score 0.88
  • 6EPD · Substrate processing state 26S proteasome (SPS1) · an experimental structure of the same protein · chain A against G, TM-score 0.88

Analyse

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