AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 19 (Q9UMS4)

Structure

1 distinct chain · 22% helix, 33% strand (DSSP).

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Compared structures

• 4LG8 · Crystal structure of PRPF19 WD40 repeats · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 4LG8 · Crystal structure of PRPF19 WD40 repeats · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 8C6J · Human spliceosomal PM5 C* complex · an experimental structure of the same protein · chain A against v, TM-score 0.24
• 8RO2 · Integrative Structure of the human intron lariat Spliceosome (ILS'') · an experimental structure of the same protein · chain A against s, TM-score 0.24
• 8I0V · The cryo-EM structure of human post-Bact complex · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 8I0U · The cryo-EM structure of human Bact-IV complex · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 7W59 · The cryo-EM structure of human pre-C*-I complex · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 7W5A · The cryo-EM structure of human pre-C*-II complex · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 7W5A · The cryo-EM structure of human pre-C*-II complex · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 5XJC · Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom · an experimental structure of the same protein · chain A against r, TM-score 0.24
• 6ID1 · Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex)… · an experimental structure of the same protein · chain A against r, TM-score 0.24

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9UMS4
• Elsewhere: UniProt Q9UMS4 · AlphaFold DB Q9UMS4