MolNFT v1 · #303947 · protein
AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase 1, mitochondrial (Q8TCS8)
Q8TCS8: “AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase 1, mitochondrial (Q8TCS8)”. 7 pockets (best druggability 0.79). MolNFT v1 #303947 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TCS8
- Type
- protein
- Length
- 783 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd6bC1C645b7B141A4643641CCE4f692185f8f8FC
- Molecule
- Polyribonucleotide nucleotidyltransferase 1, mitochondrial
- UniProt
- Q8TCS8
- Pockets
- 7 · best druggability 0.79
Structure
1 distinct chain · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polyribonucleotide nucleotidyltransferase 1, mitochondrial | protein | 783 | 33% helix, 25% strand | Q8TCS8 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1033 | 0.79 | 0.81 | 73 | empty |
| 2 | 725 | 0.66 | 0.75 | 71 | empty |
| 3 | 224 | 0.55 | 0.78 | 27 | empty |
| 4 | 93 | 0.48 | 0.82 | 17 | empty |
| 5 | 111 | 0.37 | 0.74 | 24 | empty |
Compared structures
- 3U1K · Crystal structure of human pnpase · an experimental structure of the same protein · chain A against C, TM-score 0.78
- 3U1K · Crystal structure of human PNPase · an experimental structure of the same protein · chain A against C, TM-score 0.78
- 5ZF6 · Crystal structure of the dimeric human pnpase · an experimental structure of the same protein · chain A against A, TM-score 0.71
- 5ZF6 · Crystal structure of the dimeric human PNPase · an experimental structure of the same protein · chain A against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TCS8
- Elsewhere: UniProt Q8TCS8 · AlphaFold DB Q8TCS8
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