UniProt Q8TCS8
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (Q8TCS8)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (UniProt Q8TCS8), EC 2.7.7.8: 4 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8TCS8
- Protein
- Polyribonucleotide nucleotidyltransferase 1, mitochondrial
- EC
- 2.7.7.8
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 17 · 2 records with a druggable one
Structures
5 records of Q8TCS8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3U1K | Crystal structure of human PNPase | x-ray diffraction | A, C, B, D | — | — |
| 3U1K | Crystal structure of human pnpase | x-ray diffraction | A, C, B, D | — | — |
| 5ZF6 | Crystal structure of the dimeric human PNPase | x-ray diffraction | A, B | — | 10 (best 0.62) |
| 5ZF6 | Crystal structure of the dimeric human pnpase | x-ray diffraction | A, B | — | — |
| Q8TCS8 | AlphaFold monomer V2.0 prediction for polyribonucleotide nucleotidyltransferase 1, mitochondrial… | predicted | A | — | 7 (best 0.79) |
Experiment against prediction
- 5ZF6 chain B against the predicted model Q8TCS8: TM-score 0.99, RMSD 0.92 Å
- 5ZF6 chain B against the predicted model Q8TCS8: TM-score 0.99, RMSD 0.92 Å
- 5ZF6 chain A against the predicted model Q8TCS8: TM-score 0.99, RMSD 1.02 Å
- 5ZF6 chain A against the predicted model Q8TCS8: TM-score 0.99, RMSD 1.02 Å
- 3U1K chain B against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.28 Å
- 3U1K chain B against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.28 Å
- 3U1K chain D against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.34 Å
- 3U1K chain D against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.34 Å
- 3U1K chain A against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.37 Å
- 3U1K chain A against the predicted model Q8TCS8: TM-score 0.98, RMSD 1.37 Å
Elsewhere
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