MolNFT v1 · #299360 · protein
AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase PIF1 (Q9H611)
Q9H611: “AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase PIF1 (Q9H611)”. 7 pockets (best druggability 0.77). MolNFT v1 #299360 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9H611
- Type
- protein
- Length
- 641 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- ATP-dependent DNA helicase PIF1
- UniProt
- Q9H611
- Pockets
- 7 · best druggability 0.77
Structure
1 distinct chain · 29% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent DNA helicase PIF1 | protein | 641 | 29% helix, 23% strand | Q9H611 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 905 | 0.77 | 0.80 | 74 | empty |
| 2 | 163 | 0.54 | 0.80 | 29 | empty |
| 3 | 227 | 0.51 | 0.76 | 32 | empty |
| 4 | 185 | 0.45 | 0.74 | 30 | empty |
| 5 | 73 | 0.33 | 0.75 | 17 | empty |
Compared structures
- 6HPH · Crystal structure of human Pif1 helicase in complex with AMP-PNP · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 6HPH · Crystal structure of human PIF1 helicase in complex with AMP-pnp · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 9FI9 · Human PIF + Z48847594 (OCCUPANCY 0.7) · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 9FB8 · XChem refined PIF1-x0076 complex · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6HPQ · Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form. · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6HPQ · Crystal structure of human PIF1 helicase in complex with AMP-pnp, brominated crystal form. · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6HPU · Crystal structure of human Pif1 helicase in complex with ADP-AlF4 · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 6HPU · Crystal structure of human PIF1 helicase in complex with ADP-ALF4 · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 6HPT · Crystal structure of human PIF1 helicase, apoform. · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 6HPT · Crystal structure of human Pif1 helicase, apoform. · an experimental structure of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H611
- Elsewhere: UniProt Q9H611 · AlphaFold DB Q9H611
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