UniProt Q9H611
ATP-dependent DNA helicase PIF1 (Q9H611)
ATP-dependent DNA helicase PIF1 (UniProt Q9H611): 9 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H611
- Protein
- ATP-dependent DNA helicase PIF1
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 7 · 1 record with a druggable one
Structures
10 records of Q9H611 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FHH | Structure of human Pif1 helicase domain residues 200-641 | x-ray diffraction | A, B | ADP, ALF | — |
| 5FHH | Structure of human PIF1 helicase domain residues 200-641 | x-ray diffraction | A, B | — | — |
| 6HPH | Crystal structure of human PIF1 helicase in complex with AMP-pnp | x-ray diffraction | A | ANP, MG | — |
| 6HPQ | Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form. | x-ray diffraction | A, B | ANP, MG, BR | — |
| 6HPQ | Crystal structure of human PIF1 helicase in complex with AMP-pnp, brominated crystal form. | x-ray diffraction | A, B | ANP, MG, BR | — |
| 6HPT | Crystal structure of human Pif1 helicase, apoform. | x-ray diffraction | A | SO4 | — |
| 6HPT | Crystal structure of human PIF1 helicase, apoform. | x-ray diffraction | A | SO4 | — |
| 6HPU | Crystal structure of human Pif1 helicase in complex with ADP-AlF4 | x-ray diffraction | A, B | ADP, ALF, MG | — |
| 6HPU | Crystal structure of human PIF1 helicase in complex with ADP-ALF4 | x-ray diffraction | A, B | ADP, ALF, MG | — |
| Q9H611 | AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase PIF1 (Q9H611) | predicted | A | — | 7 (best 0.77) |
Ligands
Experiment against prediction
- 6HPH chain A against the predicted model Q9H611: TM-score 0.99, RMSD 0.99 Å
- 6HPQ chain A against the predicted model Q9H611: TM-score 0.98, RMSD 1.05 Å
- 6HPQ chain A against the predicted model Q9H611: TM-score 0.98, RMSD 1.05 Å
- 6HPT chain A against the predicted model Q9H611: TM-score 0.97, RMSD 1.45 Å
- 6HPT chain A against the predicted model Q9H611: TM-score 0.97, RMSD 1.45 Å
- 6HPU chain A against the predicted model Q9H611: TM-score 0.96, RMSD 1.51 Å
- 6HPU chain A against the predicted model Q9H611: TM-score 0.96, RMSD 1.51 Å
- 6HPU chain B against the predicted model Q9H611: TM-score 0.96, RMSD 1.50 Å
- 6HPU chain B against the predicted model Q9H611: TM-score 0.96, RMSD 1.50 Å
- 5FHH chain A against the predicted model Q9H611: TM-score 0.96, RMSD 1.50 Å
Elsewhere
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