MolNFT v1 · #292927 · protein
AlphaFold monomer V2.0 prediction for astrocytic phosphoprotein pea-15 (Q15121)
Q15121: “AlphaFold monomer V2.0 prediction for astrocytic phosphoprotein pea-15 (Q15121)”. 1 pocket (best druggability 0.49). MolNFT v1 #292927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15121
- Type
- protein
- Length
- 130 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB5337bAf208B901b77517FD7A038257Cee30A7e4
- Molecule
- Astrocytic phosphoprotein pea-15
- UniProt
- Q15121
- Pockets
- 1 · best druggability 0.49
Structure
1 distinct chain · 54% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Astrocytic phosphoprotein pea-15 | protein | 130 | 54% helix, 2% strand | Q15121 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 155 | 0.49 | 0.78 | 19 | empty |
Compared structures
- 4IZA · Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain · an experimental structure of the same protein · chain A against B, TM-score 0.63
- 4IZA · Structure of dually phosphorylated ERK2 bound to the pea-15 death effector domain · an experimental structure of the same protein · chain A against B, TM-score 0.63
- 6P6B · Cs-rosetta model of pea-15 death effector domain · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 6P6B · CS-Rosetta Model of PEA-15 Death Effector Domain · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 4IZ5 · Structure of the complex between ERK2 phosphomimetic mutant and pea-15 · an experimental structure of the same protein · chain A against E, TM-score 0.60
- 4IZ5 · Structure of the complex between ERK2 phosphomimetic mutant and PEA-15 · an experimental structure of the same protein · chain A against E, TM-score 0.60
- 6P6C · Cs-rosetta model of pea-15 death effector domain in the complex with ERK2 · an experimental structure of the same protein · chain A against A, TM-score 0.47
- 6P6C · CS-Rosetta Model of PEA-15 Death Effector Domain in the Complex with ERK2 · an experimental structure of the same protein · chain A against A, TM-score 0.47
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15121
- Elsewhere: UniProt Q15121 · AlphaFold DB Q15121
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