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AlphaFold monomer V2.0 prediction for astrocytic phosphoprotein pea-15 (Q15121)

Analyse AlphaFold monomer V2.0 prediction for astrocytic phosphoprotein pea-15 (Q15121) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q15121
Type
protein
Length
130 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB5337bAf208B901b77517FD7A038257Cee30A7e4
Molecule
Astrocytic phosphoprotein pea-15
UniProt
Q15121
Pockets
1 · best druggability 0.49

Structure

1 distinct chain · 54% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAstrocytic phosphoprotein pea-15protein13054% helix, 2% strandQ15121

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11550.490.7819empty

Compared structures

  • 4IZA · Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain · an experimental structure of the same protein · chain A against B, TM-score 0.63
  • 4IZA · Structure of dually phosphorylated ERK2 bound to the pea-15 death effector domain · an experimental structure of the same protein · chain A against B, TM-score 0.63
  • 6P6B · Cs-rosetta model of pea-15 death effector domain · an experimental structure of the same protein · chain A against A, TM-score 0.63
  • 6P6B · CS-Rosetta Model of PEA-15 Death Effector Domain · an experimental structure of the same protein · chain A against A, TM-score 0.63
  • 4IZ5 · Structure of the complex between ERK2 phosphomimetic mutant and pea-15 · an experimental structure of the same protein · chain A against E, TM-score 0.60
  • 4IZ5 · Structure of the complex between ERK2 phosphomimetic mutant and PEA-15 · an experimental structure of the same protein · chain A against E, TM-score 0.60
  • 6P6C · Cs-rosetta model of pea-15 death effector domain in the complex with ERK2 · an experimental structure of the same protein · chain A against A, TM-score 0.47
  • 6P6C · CS-Rosetta Model of PEA-15 Death Effector Domain in the Complex with ERK2 · an experimental structure of the same protein · chain A against A, TM-score 0.47

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