MolNFT v1 · #285008 · protein
AlphaFold monomer V2.0 prediction for cytosolic phospholipase A2 delta (Q86XP0)
Q86XP0: “AlphaFold monomer V2.0 prediction for cytosolic phospholipase A2 delta (Q86XP0)”. 9 pockets (best druggability 0.74). MolNFT v1 #285008 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q86XP0
- Type
- protein
- Length
- 818 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Cytosolic phospholipase A2 delta
- UniProt
- Q86XP0
- Pockets
- 9 · best druggability 0.74
Structure
1 distinct chain · 30% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytosolic phospholipase A2 delta | protein | 818 | 30% helix, 26% strand | Q86XP0 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.74 | 0.96 | 24 | empty |
| 2 | 110 | 0.63 | 0.88 | 26 | empty |
| 3 | 195 | 0.54 | 0.79 | 32 | empty |
| 4 | 184 | 0.51 | 0.78 | 30 | empty |
| 5 | 88 | 0.51 | 0.83 | 20 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5IZ5 · Human givd cytosolic phospholipase A2 · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 5IZ5 · Human GIVD cytosolic phospholipase A2 · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 5IZR · Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl… · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 5IZR · Human givd cytosolic phospholipase A2 in complex with methyl gamma- linolenyl… · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 5IXC · Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl… · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 5IXC · Human givd cytosolic phospholipase A2 in complex with methyl gamma- linolenyl… · an experimental structure of the same protein · chain A against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86XP0
- Elsewhere: UniProt Q86XP0 · AlphaFold DB Q86XP0
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