UniProt Q86XP0
Cytosolic phospholipase A2 delta (Q86XP0)
Cytosolic phospholipase A2 delta (UniProt Q86XP0), EC 3.1.1.4: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q86XP0
- Protein
- Cytosolic phospholipase A2 delta
- EC
- 3.1.1.4
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 43 · 3 records with a druggable one
Structures
7 records of Q86XP0 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IXC | Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate | x-ray diffraction | A, B | 7FA, BA | 18 (best 0.85) |
| 5IXC | Human givd cytosolic phospholipase A2 in complex with methyl gamma- linolenyl fluorophosphonate | x-ray diffraction | A, B | — | — |
| 5IZ5 | Human GIVD cytosolic phospholipase A2 | x-ray diffraction | B, A | SO4 | 16 (best 0.79) |
| 5IZ5 | Human givd cytosolic phospholipase A2 | x-ray diffraction | B, A | — | — |
| 5IZR | Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate… | x-ray diffraction | A, B, C, D | 7FA, TB | — |
| 5IZR | Human givd cytosolic phospholipase A2 in complex with methyl gamma- linolenyl fluorophosphonate… | x-ray diffraction | A, B, C, D | — | — |
| Q86XP0 | AlphaFold monomer V2.0 prediction for cytosolic phospholipase A2 delta (Q86XP0) | predicted | A | — | 9 (best 0.74) |
Ligands
Experiment against prediction
- 5IZ5 chain A against the predicted model Q86XP0: TM-score 1.00, RMSD 0.46 Å
- 5IZ5 chain A against the predicted model Q86XP0: TM-score 1.00, RMSD 0.46 Å
- 5IZR chain B against the predicted model Q86XP0: TM-score 0.94, RMSD 2.45 Å
- 5IZR chain B against the predicted model Q86XP0: TM-score 0.94, RMSD 2.45 Å
- 5IZR chain C against the predicted model Q86XP0: TM-score 0.94, RMSD 2.39 Å
- 5IZR chain C against the predicted model Q86XP0: TM-score 0.94, RMSD 2.39 Å
- 5IZR chain D against the predicted model Q86XP0: TM-score 0.94, RMSD 2.42 Å
- 5IZR chain D against the predicted model Q86XP0: TM-score 0.94, RMSD 2.42 Å
- 5IZR chain A against the predicted model Q86XP0: TM-score 0.94, RMSD 2.52 Å
- 5IZR chain A against the predicted model Q86XP0: TM-score 0.94, RMSD 2.52 Å
Elsewhere
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