GL1X · GenesisL1 explorer

MolNFT v1 · #277424 · protein

AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP85 (Q9BW27)

Q9BW27: “AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP85 (Q9BW27)”. 4 pockets (best druggability 0.54). MolNFT v1 #277424 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9BW27
Type
protein
Length
656 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
Nuclear pore complex protein NUP85
UniProt
Q9BW27
Pockets
4 · best druggability 0.54

Structure

1 distinct chain · 67% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear pore complex protein NUP85protein65667% helix, 1% strandQ9BW27

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11560.540.8025empty
2710.520.8518empty
3910.340.7419empty
4840.320.7311empty

Compared structures

  • 7PEQ · Model of the outer rings of the human nuclear pore complex · an experimental structure of the same protein · chain A against AH, TM-score 0.63
  • 5A9Q · Human nuclear pore complex · an experimental structure of the same protein · chain A against 8, TM-score 0.54
  • 5A9Q · Human nuclear pore complex · an experimental structure of the same protein · chain A against 8, TM-score 0.54

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