UniProt Q9BW27

Nuclear pore complex protein Nup85 (Q9BW27)

Nuclear pore complex protein Nup85 (UniProt Q9BW27): 5 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9BW27
Protein: Nuclear pore complex protein Nup85
Experimental structures: 5
Predicted models: 1
Pockets: 19 · 4 records with a druggable one

Structures

6 records of Q9BW27 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5A9Q	Human nuclear pore complex	electron microscopy	8, H, Q, Z	—	—
5A9Q	Human nuclear pore complex	electron microscopy	8, H, Q, Z	—	—
7PEQ	Model of the outer rings of the human nuclear pore complex	electron microscopy	AH, BH, CH, DH	—	5 (best 0.78)
7R5J	Human nuclear pore complex (dilated)	electron microscopy	P0, P1, P2, P3	—	6 (best 0.84)
7R5K	Human nuclear pore complex (constricted)	electron microscopy	P0, P1, P2, P3	—	4 (best 0.85)
Q9BW27	AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP85 (Q9BW27)	predicted	A	—	4 (best 0.54)

Experiment against prediction

7R5J chain P1 against the predicted model Q9BW27: TM-score 0.91, RMSD 2.68 Å
7R5K chain P3 against the predicted model Q9BW27: TM-score 0.91, RMSD 2.67 Å
7R5K chain P1 against the predicted model Q9BW27: TM-score 0.91, RMSD 2.80 Å
7R5K chain P2 against the predicted model Q9BW27: TM-score 0.90, RMSD 2.91 Å
7R5J chain P2 against the predicted model Q9BW27: TM-score 0.90, RMSD 2.63 Å
7R5J chain P0 against the predicted model Q9BW27: TM-score 0.90, RMSD 2.86 Å
7R5K chain P0 against the predicted model Q9BW27: TM-score 0.89, RMSD 3.07 Å
7R5J chain P3 against the predicted model Q9BW27: TM-score 0.88, RMSD 3.21 Å
5A9Q chain 8 against the predicted model Q9BW27: TM-score 0.78, RMSD 4.03 Å
5A9Q chain 8 against the predicted model Q9BW27: TM-score 0.78, RMSD 4.03 Å

Elsewhere

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