MolNFT v1 · #273828 · protein
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 6 (O78757)
O78757: “AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 6 (O78757)”. 1 pocket (best druggability 0.54). MolNFT v1 #273828 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O78757
- Type
- protein
- Length
- 175 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x99b776DEB2a7E235736ca77F71997f7A305AC803
- Molecule
- NADH-ubiquinone oxidoreductase chain 6
- UniProt
- O78757
- Pockets
- 1 · best druggability 0.54
Structure
1 distinct chain · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 6 | protein | 175 | 70% helix, 0% strand | O78757 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 289 | 0.54 | 0.75 | 33 | empty |
Compared structures
- 6ZKK · Complex I inhibited by rotenone, closed · an experimental structure of the same protein · chain A against J, TM-score 0.90
- 6ZKO · Native complex I, closed · an experimental structure of the same protein · chain A against J, TM-score 0.90
- 6ZKB · Membrane domain of closed complex I during turnover · an experimental structure of the same protein · chain A against J, TM-score 0.89
- 6ZKC · Complex I during turnover, closed · an experimental structure of the same protein · chain A against J, TM-score 0.89
- 6ZKG · Complex I with NADH, closed · an experimental structure of the same protein · chain A against J, TM-score 0.89
- 6ZKI · Complex I with NADH, OPEN2 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 6ZKE · Complex I during turnover, OPEN2 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 6ZKF · Complex I during turnover, OPEN3 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 6ZKJ · Complex I with NADH, OPEN3 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 6ZKH · Complex I with NADH, OPEN1 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 6ZKD · Complex I during turnover, OPEN1 · an experimental structure of the same protein · chain A against J, TM-score 0.87
- 7ZDP · Complex I from Ovis aries at pH9, Open state · an experimental structure of the same protein · chain A against J, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O78757
- Elsewhere: UniProt O78757 · AlphaFold DB O78757
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