UniProt O78757
NADH-ubiquinone oxidoreductase chain 6 (O78757)
NADH-ubiquinone oxidoreductase chain 6 (UniProt O78757), EC 7.1.1.2: 34 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 34 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O78757
- Protein
- NADH-ubiquinone oxidoreductase chain 6
- EC
- 7.1.1.2
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 34 · 9 records with a druggable one
Structures
35 records of O78757 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LNK | Entire ovine respiratory complex I | electron microscopy | J | PC1, CDL, 3PE | — |
| 5LNK | Entire ovine respiratory complex I | electron microscopy | J | PC1, CDL, 3PE | — |
| 6ZKA | Membrane domain of open complex I during turnover | electron microscopy | J | PC1, 3PE | — |
| 6ZKB | Membrane domain of closed complex I during turnover | electron microscopy | J | 3PE | 3 (best 0.90) |
| 6ZKB | Membrane domain of closed complex I during turnover | electron microscopy | J | 3PE | — |
| 6ZKC | Complex I during turnover, closed | electron microscopy | J | 3PE | 6 (best 0.88) |
| 6ZKC | Complex I during turnover, closed | electron microscopy | J | 3PE | — |
| 6ZKD | Complex I during turnover, OPEN1 | electron microscopy | J | PC1, 3PE | — |
| 6ZKE | Complex I during turnover, OPEN2 | electron microscopy | J | PC1, 3PE | — |
| 6ZKF | Complex I during turnover, open3 | electron microscopy | J | PC1, 3PE | 3 (best 0.90) |
| 6ZKF | Complex I during turnover, OPEN3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKG | Complex I with NADH, closed | electron microscopy | J | 3PE | — |
| 6ZKH | Complex I with NADH, open1 | electron microscopy | J | PC1, 3PE | 4 (best 0.90) |
| 6ZKH | Complex I with NADH, OPEN1 | electron microscopy | J | PC1, 3PE | — |
| 6ZKI | Complex I with NADH, OPEN2 | electron microscopy | J | PC1, 3PE | — |
| 6ZKJ | Complex I with NADH, OPEN3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKK | Complex I inhibited by rotenone, closed | electron microscopy | J | 3PE | — |
| 6ZKL | Complex I inhibited by rote , open1 | electron microscopy | J | PC1, 3PE | 3 (best 0.90) |
| 6ZKL | Complex I inhibited by rotenone, OPEN1 | electron microscopy | J | PC1, 3PE | — |
| 6ZKM | Complex I inhibited by rotenone, OPEN2 | electron microscopy | J | PC1, 3PE | — |
| 6ZKN | Complex I inhibited by rotenone, OPEN3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKO | Native complex I, closed | electron microscopy | J | 3PE | — |
| 6ZKP | Native complex I, OPEN1 | electron microscopy | J | PC1, 3PE | — |
| 6ZKQ | Native complex I, OPEN2 | electron microscopy | J | PC1, 3PE | — |
| 6ZKR | Native complex I, open3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKR | Native complex I, OPEN3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKS | Deactive complex I, OPEN1 | electron microscopy | J | PC1, 3PE | — |
| 6ZKT | Deactive complex I, open2 | electron microscopy | J | PC1, 3PE | 5 (best 0.86) |
| 6ZKT | Deactive complex I, OPEN2 | electron microscopy | J | PC1, 3PE | — |
| 6ZKU | Deactive complex I, open3 | electron microscopy | J | PC1, 3PE | 4 (best 0.86) |
| 6ZKU | Deactive complex I, OPEN3 | electron microscopy | J | PC1, 3PE | — |
| 6ZKV | Deactive complex I, open4 | electron microscopy | J | PC1, 3PE | 5 (best 0.85) |
| 6ZKV | Deactive complex I, OPEN4 | electron microscopy | J | PC1, 3PE | — |
| 7ZDP | Complex I from Ovis aries at pH9, Open state | electron microscopy | J | — | — |
| O78757 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 6 (O78757) | predicted | A | — | 1 (best 0.54) |
Ligands
Experiment against prediction
- 6ZKP chain J against the predicted model O78757: TM-score 0.90, RMSD 2.06 Å
- 6ZKR chain J against the predicted model O78757: TM-score 0.90, RMSD 2.04 Å
- 6ZKR chain J against the predicted model O78757: TM-score 0.90, RMSD 2.04 Å
- 6ZKA chain J against the predicted model O78757: TM-score 0.90, RMSD 2.10 Å
- 6ZKI chain J against the predicted model O78757: TM-score 0.90, RMSD 2.11 Å
- 6ZKE chain J against the predicted model O78757: TM-score 0.90, RMSD 2.12 Å
- 6ZKL chain J against the predicted model O78757: TM-score 0.90, RMSD 2.07 Å
- 6ZKL chain J against the predicted model O78757: TM-score 0.90, RMSD 2.07 Å
- 6ZKF chain J against the predicted model O78757: TM-score 0.90, RMSD 2.12 Å
- 6ZKF chain J against the predicted model O78757: TM-score 0.90, RMSD 2.12 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.