MolNFT v1 · #273347 · protein
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 4 (O78755)
O78755: “AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 4 (O78755)”. 3 pockets (best druggability 0.61). MolNFT v1 #273347 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O78755
- Type
- protein
- Length
- 459 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xEa0B57aD486d6137BB24F190997CF1329746695b
- Molecule
- NADH-ubiquinone oxidoreductase chain 4
- UniProt
- O78755
- Pockets
- 3 · best druggability 0.61
Structure
1 distinct chain · 76% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 4 | protein | 459 | 76% helix, 3% strand | O78755 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.61 | 0.79 | 37 | empty |
| 2 | 105 | 0.56 | 0.84 | 15 | empty |
| 3 | 75 | 0.31 | 0.74 | 18 | empty |
Compared structures
- 6ZKP · Native complex I, open1 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKP · Native complex I, OPEN1 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKJ · Complex I with NADH, open3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKJ · Complex I with NADH, OPEN3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 7ZDJ · Complex I from Ovis aries at pH5.5, Open state · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKQ · Native complex I, open2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKQ · Native complex I, OPEN2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKF · Complex I during turnover, open3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKF · Complex I during turnover, OPEN3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 7ZD6 · Complex I from Ovis aries, at pH7.4, Open state · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKT · Deactive complex I, OPEN2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
- 6ZKT · Deactive complex I, open2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O78755
- Elsewhere: UniProt O78755 · AlphaFold DB O78755
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