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AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 4 (O78755)

Analyse AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 4… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O78755
Type
protein
Length
459 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xEa0B57aD486d6137BB24F190997CF1329746695b
Molecule
NADH-ubiquinone oxidoreductase chain 4
UniProt
O78755
Pockets
3 · best druggability 0.61

Structure

1 distinct chain · 76% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH-ubiquinone oxidoreductase chain 4protein45976% helix, 3% strandO78755

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12870.610.7937empty
21050.560.8415empty
3750.310.7418empty

Compared structures

  • 6ZKP · Native complex I, open1 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKP · Native complex I, OPEN1 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKJ · Complex I with NADH, open3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKJ · Complex I with NADH, OPEN3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 7ZDJ · Complex I from Ovis aries at pH5.5, Open state · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKQ · Native complex I, open2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKQ · Native complex I, OPEN2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKF · Complex I during turnover, open3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKF · Complex I during turnover, OPEN3 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 7ZD6 · Complex I from Ovis aries, at pH7.4, Open state · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKT · Deactive complex I, OPEN2 · an experimental structure of the same protein · chain A against M, TM-score 0.99
  • 6ZKT · Deactive complex I, open2 · an experimental structure of the same protein · chain A against M, TM-score 0.99

Analyse

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