MolNFT v1 · #272311 · protein
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 2 (O79875)
O79875: “AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 2 (O79875)”. 3 pockets (best druggability 0.32). MolNFT v1 #272311 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O79875
- Type
- protein
- Length
- 347 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4F3500FD13628563884A773578190b4E4dCd3a28
- Molecule
- NADH-ubiquinone oxidoreductase chain 2
- UniProt
- O79875
- Pockets
- 3 · best druggability 0.32
Structure
1 distinct chain · 76% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 2 | protein | 347 | 76% helix, 1% strand | O79875 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.32 | 0.76 | 14 | empty |
| 2 | 76 | 0.32 | 0.73 | 16 | empty |
| 3 | 53 | 0.29 | 0.75 | 13 | empty |
Compared structures
- 7VC0 · Membrane arm of active state ci from rotenone-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 1.00
- 7V33 · Active state complex I from rotenone-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V31 · Active state complex I from rotenone dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V2R · Active state complex I from Q1-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7VXS · Membrane arm of active state CI from Q10 dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V2C · Active state complex I from Q10 dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7VBL · Membrane arm of active state ci from dq-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V2H · Active state complex I from dq-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7W2R · Active state CI from DQ-NADH dataset, Subclass 1 · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V2E · Active state complex I from Q10-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7W4G · Active state CI from Q1-NADH dataset, Subclass 5 · an experimental structure of the same protein · chain A against i, TM-score 0.99
- 7V32 · Deactive state complex I from rotenone dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O79875
- Elsewhere: UniProt O79875 · AlphaFold DB O79875
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