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AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 2 (O79875)

Analyse AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O79875
Type
protein
Length
347 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4F3500FD13628563884A773578190b4E4dCd3a28
Molecule
NADH-ubiquinone oxidoreductase chain 2
UniProt
O79875
Pockets
3 · best druggability 0.32

Structure

1 distinct chain · 76% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH-ubiquinone oxidoreductase chain 2protein34776% helix, 1% strandO79875

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.320.7614empty
2760.320.7316empty
3530.290.7513empty

Compared structures

  • 7VC0 · Membrane arm of active state CI from Rote -NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 1.00
  • 7VC0 · Membrane arm of active state ci from rotenone-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 1.00
  • 7VYS · Membrane arm of active state CI from Q1-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 1.00
  • 7V33 · Active state complex I from rote -NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7V33 · Active state complex I from rotenone-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7W1T · Active state CI from Rote dataset, Subclass 1 · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7W1U · Active state CI from Rote dataset, Subclass 2 · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7VYG · Membrane arm of active state CI from rote dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7V31 · Active state complex I from rotenone dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7V31 · Active state complex I from rote dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7W1V · Active state CI from Rote -NADH dataset, Subclass 1 · an experimental structure of the same protein · chain A against i, TM-score 0.99
  • 7V2R · Active state complex I from Q1-NADH dataset · an experimental structure of the same protein · chain A against i, TM-score 0.99

Analyse

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