MolNFT v1 · #271672 · protein
AlphaFold monomer V2.0 prediction for nucleoporin NUP159 (P40477)
P40477: “AlphaFold monomer V2.0 prediction for nucleoporin NUP159 (P40477)”. 3 pockets (best druggability 0.80). MolNFT v1 #271672 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40477
- Type
- protein
- Length
- 1,460 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Nucleoporin NUP159
- UniProt
- P40477
- Pockets
- 3 · best druggability 0.80
Structure
1 distinct chain · 18% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP159 | protein | 1460 | 18% helix, 14% strand | P40477 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 432 | 0.80 | 0.88 | 53 | empty |
| 2 | 110 | 0.45 | 0.78 | 13 | empty |
| 3 | 72 | 0.37 | 0.78 | 14 | empty |
Compared structures
- 3RRM · S. cerevisiae DBP5 L327V bound to NUP159, GLE1 H337R, IP6 and ADP · an experimental structure of the same protein · chain A against C, TM-score 0.25
- 3RRM · S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp · an experimental structure of the same protein · chain A against C, TM-score 0.25
- 1XIP · Crystal Structure of the N-terminal Domain of Nup159 · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 1XIP · Crystal structure of the N-terminal domain of NUP159 · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 3PBP · Structure of the yeast heterotrimeric Nup82-Nup159-Nup116 nucleoporin complex · an experimental structure of the same protein · chain A against I, TM-score 0.02
- 3PBP · Structure of the yeast heterotrimeric NUP82-NUP159-NUP116 nucleoporin complex · an experimental structure of the same protein · chain A against I, TM-score 0.02
- 3TKN · Structure of the Nup82-Nup159-Nup98 heterotrimer · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 3TKN · Structure of the NUP82-NUP159-NUP98 heterotrimer · an experimental structure of the same protein · chain A against B, TM-score 0.02
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40477
- Elsewhere: UniProt P40477 · AlphaFold DB P40477
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