UniProt P40477
Nucleoporin NUP159 (P40477)
Nucleoporin NUP159 (UniProt P40477): 11 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40477
- Protein
- Nucleoporin NUP159
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
12 records of P40477 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XIP | Crystal Structure of the N-terminal Domain of Nup159 | x-ray diffraction | A | — | — |
| 1XIP | Crystal structure of the N-terminal domain of NUP159 | x-ray diffraction | A | — | — |
| 3PBP | Structure of the yeast heterotrimeric Nup82-Nup159-Nup116 nucleoporin complex | x-ray diffraction | C, F, I, L | — | — |
| 3PBP | Structure of the yeast heterotrimeric NUP82-NUP159-NUP116 nucleoporin complex | x-ray diffraction | C, F, I, L | — | — |
| 3RRM | S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp | x-ray diffraction | C | — | — |
| 3RRM | S. cerevisiae DBP5 L327V bound to NUP159, GLE1 H337R, IP6 and ADP | x-ray diffraction | C | — | — |
| 3TKN | Structure of the Nup82-Nup159-Nup98 heterotrimer | x-ray diffraction | B, E, H | — | — |
| 3TKN | Structure of the NUP82-NUP159-NUP98 heterotrimer | x-ray diffraction | B, E, H | — | — |
| 4DS1 | The Structure of a Yeast Dyn2-Nup159 Complex and the Molecular Basis for the Dynein Light Chain… | x-ray diffraction | B, D | — | — |
| 4DS1 | The structure of a yeast DYN2-NUP159 complex and the molecular basis for the dynein light chain… | x-ray diffraction | B, D | — | — |
| 7N9F | Structure of the in situ yeast NPC | electron microscopy | w, x | — | — |
| P40477 | AlphaFold monomer V2.0 prediction for nucleoporin NUP159 (P40477) | predicted | A | — | 3 (best 0.80) |
Experiment against prediction
- 1XIP chain A against the predicted model P40477: TM-score 1.00, RMSD 0.45 Å
- 1XIP chain A against the predicted model P40477: TM-score 1.00, RMSD 0.45 Å
- 3RRM chain C against the predicted model P40477: TM-score 0.99, RMSD 0.46 Å
- 3RRM chain C against the predicted model P40477: TM-score 0.99, RMSD 0.46 Å
- 3PBP chain I against the predicted model P40477: TM-score 0.81, RMSD 0.63 Å
- 3PBP chain I against the predicted model P40477: TM-score 0.81, RMSD 0.63 Å
- 3PBP chain L against the predicted model P40477: TM-score 0.79, RMSD 0.57 Å
- 3PBP chain L against the predicted model P40477: TM-score 0.79, RMSD 0.57 Å
- 3PBP chain C against the predicted model P40477: TM-score 0.76, RMSD 1.21 Å
- 3PBP chain C against the predicted model P40477: TM-score 0.76, RMSD 1.21 Å
Elsewhere
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