MolNFT v1 · #265929 · protein
AlphaFold monomer V2.0 prediction for notchless protein homolog 1 (Q9NVX2)
Q9NVX2: “AlphaFold monomer V2.0 prediction for notchless protein homolog 1 (Q9NVX2)”. 4 pockets (best druggability 0.82). MolNFT v1 #265929 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9NVX2
- Type
- protein
- Length
- 485 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Notchless protein homolog 1
- UniProt
- Q9NVX2
- Pockets
- 4 · best druggability 0.82
Structure
1 distinct chain · 9% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Notchless protein homolog 1 | protein | 485 | 9% helix, 45% strand | Q9NVX2 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.82 | 0.84 | 65 | empty |
| 2 | 874 | 0.75 | 0.79 | 68 | empty |
| 3 | 60 | 0.34 | 0.77 | 16 | empty |
| 4 | 59 | 0.27 | 0.73 | 16 | empty |
Compared structures
- 8IR3 · human nuclear pre-60S ribosomal particle - State B' · an experimental structure of the same protein · chain A against N, TM-score 0.96
- 8IR1 · human nuclear pre-60S ribosomal particle - State A · an experimental structure of the same protein · chain A against N, TM-score 0.96
- 8FL0 · Human nucleolar pre-60S ribosomal subunit (State H) · an experimental structure of the same protein · chain A against NJ, TM-score 0.94
- 8INK · human nuclear pre-60S ribosomal particle - State D · an experimental structure of the same protein · chain A against W, TM-score 0.79
- 8IPD · human nuclear pre-60S ribosomal particle - State C · an experimental structure of the same protein · chain A against W, TM-score 0.79
- 8IPY · human nuclear pre-60S ribosomal particle - State D' · an experimental structure of the same protein · chain A against W, TM-score 0.79
- 8IPX · human nuclear pre-60S ribosomal particle - State C' · an experimental structure of the same protein · chain A against W, TM-score 0.79
- 8FL3 · Human nuclear pre-60S ribosomal subunit (State I2) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78
- 8FL4 · Human nuclear pre-60S ribosomal subunit (State I3) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78
- 8FL2 · Human nuclear pre-60S ribosomal subunit (State I1) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NVX2
- Elsewhere: UniProt Q9NVX2 · AlphaFold DB Q9NVX2
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