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AlphaFold monomer V2.0 prediction for notchless protein homolog 1 (Q9NVX2)

Analyse AlphaFold monomer V2.0 prediction for notchless protein homolog 1 (Q9NVX2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9NVX2
Type
protein
Length
485 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
Molecule
Notchless protein homolog 1
UniProt
Q9NVX2
Pockets
4 · best druggability 0.82

Structure

1 distinct chain · 9% helix, 45% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANotchless protein homolog 1protein4859% helix, 45% strandQ9NVX2

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19140.820.8465empty
28740.750.7968empty
3600.340.7716empty
4590.270.7316empty

Compared structures

  • 8IR3 · human nuclear pre-60S ribosomal particle - State B' · an experimental structure of the same protein · chain A against N, TM-score 0.96
  • 8IR1 · human nuclear pre-60S ribosomal particle - State A · an experimental structure of the same protein · chain A against N, TM-score 0.96
  • 8FL0 · Human nucleolar pre-60S ribosomal subunit (State H) · an experimental structure of the same protein · chain A against NJ, TM-score 0.94
  • 8INK · human nuclear pre-60S ribosomal particle - State D · an experimental structure of the same protein · chain A against W, TM-score 0.79
  • 8IPD · human nuclear pre-60S ribosomal particle - State C · an experimental structure of the same protein · chain A against W, TM-score 0.79
  • 8IPY · human nuclear pre-60S ribosomal particle - State D' · an experimental structure of the same protein · chain A against W, TM-score 0.79
  • 8IPX · human nuclear pre-60S ribosomal particle - State C' · an experimental structure of the same protein · chain A against W, TM-score 0.79
  • 8FL3 · Human nuclear pre-60S ribosomal subunit (State I2) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78
  • 8FL4 · Human nuclear pre-60S ribosomal subunit (State I3) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78
  • 8FL2 · Human nuclear pre-60S ribosomal subunit (State I1) · an experimental structure of the same protein · chain A against NJ, TM-score 0.78

Analyse

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