UniProt Q9NVX2
Notchless protein homolog 1 (Q9NVX2)
Notchless protein homolog 1 (UniProt Q9NVX2): 10 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NVX2
- Protein
- Notchless protein homolog 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 12 · 7 records with a druggable one
Structures
11 records of Q9NVX2 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FL0 | Human nucleolar pre-60S ribosomal subunit (State H) | electron microscopy | NJ | — | 2 (best 0.87) |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | NJ | — | 1 (best 0.87) |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | NJ | — | 1 (best 0.87) |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | NJ | — | 1 (best 0.87) |
| 8INK | human nuclear pre-60S ribosomal particle - State D | electron microscopy | W | — | — |
| 8IPD | human nuclear pre-60S ribosomal particle - State C | electron microscopy | W | — | — |
| 8IPX | human nuclear pre-60S ribosomal particle - State C' | electron microscopy | W | — | — |
| 8IPY | human nuclear pre-60S ribosomal particle - State D' | electron microscopy | W | — | — |
| 8IR1 | human nuclear pre-60S ribosomal particle - State A | electron microscopy | N | — | 2 (best 0.86) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | N | — | 1 (best 0.87) |
| Q9NVX2 | AlphaFold monomer V2.0 prediction for notchless protein homolog 1 (Q9NVX2) | predicted | A | — | 4 (best 0.82) |
Experiment against prediction
- 8FL3 chain NJ against the predicted model Q9NVX2: TM-score 0.99, RMSD 0.55 Å
- 8FL4 chain NJ against the predicted model Q9NVX2: TM-score 0.99, RMSD 0.56 Å
- 8FL2 chain NJ against the predicted model Q9NVX2: TM-score 0.99, RMSD 0.56 Å
- 8INK chain W against the predicted model Q9NVX2: TM-score 0.99, RMSD 0.84 Å
- 8IR3 chain N against the predicted model Q9NVX2: TM-score 0.98, RMSD 1.00 Å
- 8IR1 chain N against the predicted model Q9NVX2: TM-score 0.98, RMSD 1.02 Å
- 8IPD chain W against the predicted model Q9NVX2: TM-score 0.98, RMSD 0.91 Å
- 8IPX chain W against the predicted model Q9NVX2: TM-score 0.98, RMSD 0.92 Å
- 8IPY chain W against the predicted model Q9NVX2: TM-score 0.98, RMSD 0.92 Å
- 8FL0 chain NJ against the predicted model Q9NVX2: TM-score 0.97, RMSD 1.51 Å
Elsewhere
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