GL1X · GenesisL1 explorer

MolNFT v1 · #265480 · protein

AlphaFold monomer V2.0 prediction for putative nickel-responsive regulator (O25896)

O25896: “AlphaFold monomer V2.0 prediction for putative nickel-responsive regulator (O25896)”. 1 pocket (best druggability 0.26). MolNFT v1 #265480 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O25896
Type
protein
Length
148 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
Molecule
Putative nickel-responsive regulator
UniProt
O25896
Pockets
1 · best druggability 0.26

Structure

1 distinct chain · 39% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APutative nickel-responsive regulatorprotein14839% helix, 25% strandO25896

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1610.260.7210empty

Compared structures

  • 2CA9 · Apo-nikr from helicobacter pylori in closed trans- conformation · an experimental structure of the same protein · chain A against B, TM-score 0.91
  • 2CA9 · apo-NIKR from helicobacter pylori in closed trans-conformation · an experimental structure of the same protein · chain A against B, TM-score 0.91
  • 2WVB · Structural and mechanistic insights into helicobacter pylori nikr function · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 2WVB · Structural and mechanistic insights into Helicobacter pylori NikR function · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 2CAJ · NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 4… · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 2CAJ · Nikr from helicobacter pylori in closed trans-conformation and nickel bound to 4… · an experimental structure of the same protein · chain A against B, TM-score 0.90
  • 2WVC · Structural and mechanistic insights into Helicobacter pylori NikR function · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 2WVC · Structural and mechanistic insights into helicobacter pylori nikr function · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 2WVF · Structural and mechanistic insights into Helicobacter pylori NikR function · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 2WVF · Structural and mechanistic insights into helicobacter pylori nikr function · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 2CAD · NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and… · an experimental structure of the same protein · chain A against B, TM-score 0.88
  • 2CAD · Nikr from helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and… · an experimental structure of the same protein · chain A against B, TM-score 0.88

Analyse

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