MolNFT v1 · #263355 · protein
AlphaFold monomer V2.0 prediction for NEUROTENSIN/NEUROMEDIN N (P20068)
P20068: “AlphaFold monomer V2.0 prediction for NEUROTENSIN/NEUROMEDIN N (P20068)”. 2 pockets (best druggability 0.34). MolNFT v1 #263355 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P20068
- Type
- protein
- Length
- 169 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x817FafA0D4e279Fbf0B85cd3Ceb78B2E511A008e
- Molecule
- NEUROTENSIN/NEUROMEDIN N
- UniProt
- P20068
- Pockets
- 2 · best druggability 0.34
Structure
1 distinct chain · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NEUROTENSIN/NEUROMEDIN N | protein | 169 | 70% helix, 0% strand | P20068 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.34 | 0.78 | 12 | empty |
| 2 | 55 | 0.26 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3ZEV · Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme… · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 3ZEV · Structure of thermostable agonist-bound neurotensin receptor 1 mutant without lysozyme… · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 4BV0 · High resolution structure of evolved agonist-bound neurotensin receptor 1 mutant without… · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 4BV0 · High Resolution Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without… · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 7L0S · Structure of nts-NTSR1-gi complex in lipid nanodisc, noncanonical state, with ahd · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 7L0R · Structure of nts-NTSR1-gi complex in lipid nanodisc, noncanonical state, without ahd · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 7L0P · Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 7L0P · Structure of nts-NTSR1-gi complex in lipid nanodisc, canonical state, without ahd · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 7L0Q · Structure of nts-NTSR1-gi complex in lipid nanodisc, canonical state, with ahd · an experimental structure of the same protein · chain A against D, TM-score 0.04
- 4BUO · High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant… · an experimental structure of the same protein · chain A against C, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20068
- Elsewhere: UniProt P20068 · AlphaFold DB P20068
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