UniProt P20068
Neurotensin (P20068)
Neurotensin (UniProt P20068): 23 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20068
- Protein
- Neurotensin
- Experimental structures
- 23
- Predicted models
- 1
- Pockets
- 10 · 4 records with a druggable one
Structures
24 records of P20068 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZEV | Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion | x-ray diffraction | C, D | — | — |
| 3ZEV | Structure of thermostable agonist-bound neurotensin receptor 1 mutant without lysozyme fusion | x-ray diffraction | C, D | — | — |
| 4BUO | High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without… | x-ray diffraction | C, D | — | — |
| 4BUO | High resolution structure of thermostable agonist-bound neurotensin receptor 1 mutant without… | x-ray diffraction | C, D | — | — |
| 4BV0 | High Resolution Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme… | x-ray diffraction | C, D | — | — |
| 4BV0 | High resolution structure of evolved agonist-bound neurotensin receptor 1 mutant without lysozyme… | x-ray diffraction | C, D | — | — |
| 4BWB | Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion | x-ray diffraction | C, D | — | — |
| 4BWB | Structure of evolved agonist-bound neurotensin receptor 1 mutant without lysozyme fusion | x-ray diffraction | C, D | — | — |
| 4XEE | Structure of active-like neurotensin receptor | x-ray diffraction | B | — | — |
| 4XEE | Structure of active-like neurotensin receptor | x-ray diffraction | B | — | — |
| 4XES | Structure of active-like neurotensin receptor | x-ray diffraction | B | — | — |
| 4XES | Structure of active-like neurotensin receptor | x-ray diffraction | B | — | — |
| 7L0P | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD | electron microscopy | D | — | 2 (best 0.71) |
| 7L0P | Structure of nts-NTSR1-gi complex in lipid nanodisc, canonical state, without ahd | electron microscopy | D | — | — |
| 7L0Q | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD | electron microscopy | D | — | 2 (best 0.71) |
| 7L0Q | Structure of nts-NTSR1-gi complex in lipid nanodisc, canonical state, with ahd | electron microscopy | D | — | — |
| 7L0R | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD | electron microscopy | D | — | 1 (best 0.34) |
| 7L0R | Structure of nts-NTSR1-gi complex in lipid nanodisc, noncanonical state, without ahd | electron microscopy | D | — | — |
| 7L0S | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD | electron microscopy | D | — | 1 (best 0.34) |
| 7L0S | Structure of nts-NTSR1-gi complex in lipid nanodisc, noncanonical state, with ahd | electron microscopy | D | — | — |
| 8FMZ | Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator | electron microscopy | F | — | — |
| 8FN0 | CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator | electron microscopy | F | — | 1 (best 0.64) |
| 8FN1 | CryoEM structure of Go-coupled NTSR1 | electron microscopy | F | — | 1 (best 0.72) |
| P20068 | AlphaFold monomer V2.0 prediction for NEUROTENSIN/NEUROMEDIN N (P20068) | predicted | A | — | 2 (best 0.34) |
Experiment against prediction
- 4BWB chain D against the predicted model P20068: TM-score 1.00, RMSD 0.02 Å
- 4BWB chain D against the predicted model P20068: TM-score 1.00, RMSD 0.02 Å
- 7L0S chain D against the predicted model P20068: TM-score 0.72, RMSD 0.33 Å
- 7L0S chain D against the predicted model P20068: TM-score 0.72, RMSD 0.33 Å
- 7L0R chain D against the predicted model P20068: TM-score 0.72, RMSD 0.33 Å
- 7L0R chain D against the predicted model P20068: TM-score 0.72, RMSD 0.33 Å
- 8FN0 chain F against the predicted model P20068: TM-score 0.70, RMSD 0.33 Å
- 4BWB chain C against the predicted model P20068: TM-score 0.64, RMSD 0.42 Å
- 4BWB chain C against the predicted model P20068: TM-score 0.64, RMSD 0.42 Å
- 7L0P chain D against the predicted model P20068: TM-score 0.63, RMSD 0.43 Å
Elsewhere
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