GL1X · GenesisL1 explorer

MolNFT v1 · #262578 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Q9CQJ8)

Q9CQJ8: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Q9CQJ8)”. 2 pockets (best druggability 0.64). MolNFT v1 #262578 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9CQJ8
Type
protein
Length
179 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
Molecule
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
UniProt
Q9CQJ8
Pockets
2 · best druggability 0.64

Structure

1 distinct chain · 55% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9protein17955% helix, 0% strandQ9CQJ8

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13320.640.7931empty
21290.380.7321empty

Compared structures

  • 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against n, TM-score 0.96
  • 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against n1, TM-score 0.96
  • 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against n, TM-score 0.96
  • 8IAQ · Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… · an experimental structure of the same protein · chain A against n, TM-score 0.95
  • 8IBD · Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against n, TM-score 0.95
  • 8IC4 · Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under… · an experimental structure of the same protein · chain A against n, TM-score 0.95
  • 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against n, TM-score 0.95
  • 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against n, TM-score 0.95
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against n, TM-score 0.94
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against n, TM-score 0.94
  • 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against n, TM-score 0.94
  • 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against n, TM-score 0.92

Analyse

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