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MolNFT v1 · #262569 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Q9D6J5)

Q9D6J5: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8…”. 2 pockets (best druggability 0.42). MolNFT v1 #262569 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9D6J5
Type
protein
Length
186 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xA8DDaf0A92150868e1cE25DA40f486Cd026B4089
Molecule
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
UniProt
Q9D6J5
Pockets
2 · best druggability 0.42

Structure

1 distinct chain · 35% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialprotein18635% helix, 2% strandQ9D6J5

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1600.420.8115empty
2630.300.7412empty

Compared structures

  • 8OM1 · Mitochondrial complex I from Mus musculus in the active state · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8RGT · Open Complex I from murine brain · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8IB6 · Respiratory complex Membrane domain of CI, focus-refined of type IA, Wild type mouse… · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8IB4 · Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against l1, TM-score 0.82
  • 8RGQ · Open Complex I from murine liver · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8PW7 · A respirasome from murine liver · an experimental structure of the same protein · chain A against l1, TM-score 0.82
  • 8PW5 · CS respirasome from murine liver · an experimental structure of the same protein · chain A against l1, TM-score 0.82
  • 7B93 · Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at… · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against l, TM-score 0.82
  • 8RGP · Closed Complex I from murine brain · an experimental structure of the same protein · chain A against l, TM-score 0.82

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