MolNFT v1 · #262566 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Q02372)
Q02372: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8…”. 2 pockets (best druggability 0.32). MolNFT v1 #262566 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q02372
- Type
- protein
- Length
- 186 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x98e22253e31B07cB0618d7388D8e56673A1A11dF
- Molecule
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
- UniProt
- Q02372
- Pockets
- 2 · best druggability 0.32
Structure
1 distinct chain · 30% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | protein | 186 | 30% helix, 2% strand | Q02372 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.32 | 0.77 | 13 | empty |
| 2 | 78 | 0.31 | 0.73 | 15 | empty |
Compared structures
- 7QSN · Bovine complex I in lipid nanodisc, Deactive-apo · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSN · Bovine complex I in lipid nanodisc, deactive-apo · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSO · Bovine complex I in lipid nanodisc, State 3 (Slack) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSO · Bovine complex I in lipid nanodisc, state 3 (slack) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7R4C · Bovine complex I in the presence of IM1761092, deactive class v (Composite map) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7R4D · Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSL · Bovine complex I in lipid nanodisc, Active-apo · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7QSL · Bovine complex I in lipid nanodisc, active-apo · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 7R43 · Bovine complex I in the presence of IM1761092, active class iii (Composite map) · an experimental structure of the same protein · chain A against l, TM-score 0.82
- 8Q46 · Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against l, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02372
- Elsewhere: UniProt Q02372 · AlphaFold DB Q02372
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