MolNFT v1 · #262470 · protein
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (P34943)
P34943: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9…”. 4 pockets (best druggability 0.79). MolNFT v1 #262470 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P34943
- Type
- protein
- Length
- 380 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8cAd045c12e1989AA602c9fc45e48bac37745e19
- Molecule
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
- UniProt
- P34943
- Pockets
- 4 · best druggability 0.79
Structure
1 distinct chain · 39% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | protein | 380 | 39% helix, 14% strand | P34943 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 488 | 0.79 | 0.86 | 47 | empty |
| 2 | 78 | 0.41 | 0.79 | 14 | empty |
| 3 | 91 | 0.34 | 0.74 | 20 | empty |
| 4 | 82 | 0.34 | 0.75 | 21 | empty |
Compared structures
- 7QSL · Bovine complex I in lipid nanodisc, active-apo · an experimental structure of the same protein · chain A against P, TM-score 0.90
- 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against P, TM-score 0.90
- 8Q0M · Outward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. · an experimental structure of the same protein · chain A against P, TM-score 0.89
- 7R41 · Bovine complex I in the presence of IM1761092, active class i (Composite map) · an experimental structure of the same protein · chain A against P, TM-score 0.89
- 7R43 · Bovine complex I in the presence of IM1761092, active class iii (Composite map) · an experimental structure of the same protein · chain A against P, TM-score 0.89
- 7R44 · Bovine complex I in the presence of IM1761092, active class iv (Composite map) · an experimental structure of the same protein · chain A against P, TM-score 0.89
- 7QSD · Bovine complex I in the active state at 3.1 a · an experimental structure of the same protein · chain A against P, TM-score 0.89
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against P, TM-score 0.88
- 8Q1Y · Outward-facing, open2 proteoliposome complex I at 2.6 A, after deactivation treatment.… · an experimental structure of the same protein · chain A against P, TM-score 0.88
- 8Q1P · Inward-facing, open2 proteoliposome complex I at 2.9 A, after deactivation treatment.… · an experimental structure of the same protein · chain A against P, TM-score 0.87
- 7QSN · Bovine complex I in lipid nanodisc, deactive-apo · an experimental structure of the same protein · chain A against P, TM-score 0.86
- 7QSO · Bovine complex I in lipid nanodisc, state 3 (slack) · an experimental structure of the same protein · chain A against P, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P34943
- Elsewhere: UniProt P34943 · AlphaFold DB P34943
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