GL1X · GenesisL1 explorer

MolNFT v1 · #262450 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Q9CQZ5)

Q9CQZ5: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Q9CQZ5)”. 1 pocket (best druggability 0.72). MolNFT v1 #262450 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9CQZ5
Type
protein
Length
131 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
Molecule
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
UniProt
Q9CQZ5
Pockets
1 · best druggability 0.72

Structure

1 distinct chain · 56% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6protein13156% helix, 0% strandQ9CQZ5

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13680.720.8337empty

Compared structures

  • 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against W1, TM-score 0.85
  • 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 8IBE · Respiratory complex Peripheral Arm of CI, focus-refined map of type II, Wild type mouse… · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 8IBD · Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 8XNP · Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IA… · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against W, TM-score 0.84
  • 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against W, TM-score 0.84

Analyse

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