GL1X · GenesisL1 explorer

MolNFT v1 · #262439 · protein

AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Q9CPP6)

Q9CPP6: “AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Q9CPP6)”. 2 pockets (best druggability 0.43). MolNFT v1 #262439 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9CPP6
Type
protein
Length
116 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
Molecule
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
UniProt
Q9CPP6
Pockets
2 · best druggability 0.43

Structure

1 distinct chain · 55% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5protein11655% helix, 0% strandQ9CPP6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1530.430.8314empty
2650.320.7514empty

Compared structures

  • 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against V, TM-score 0.96
  • 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against V, TM-score 0.96
  • 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against V1, TM-score 0.96
  • 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against V, TM-score 0.95
  • 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against V, TM-score 0.95
  • 8IAP · Respiratory complex Peripheral Arm of CI, focus-refined map of type I, Wild type mouse… · an experimental structure of the same protein · chain A against V, TM-score 0.94
  • 8XNP · Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IA… · an experimental structure of the same protein · chain A against V, TM-score 0.94
  • 8IBD · Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature · an experimental structure of the same protein · chain A against V, TM-score 0.93
  • 8IBE · Respiratory complex Peripheral Arm of CI, focus-refined map of type II, Wild type mouse… · an experimental structure of the same protein · chain A against V, TM-score 0.93
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against V, TM-score 0.93
  • 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against V, TM-score 0.93
  • 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against V, TM-score 0.92

Analyse

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