MolNFT v1 · #255623 · protein
AlphaFold monomer V2.0 prediction for unconventional myosin-VI (Q29122)
Q29122: “AlphaFold monomer V2.0 prediction for unconventional myosin-VI (Q29122)”. 15 pockets (best druggability 0.77). MolNFT v1 #255623 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q29122
- Type
- protein
- Length
- 1,254 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- Unconventional myosin-VI
- UniProt
- Q29122
- Pockets
- 15 · best druggability 0.77
Structure
1 distinct chain · 54% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Unconventional myosin-VI | protein | 1254 | 54% helix, 13% strand | Q29122 |
Pockets
15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 83 | 0.77 | 0.98 | 21 | empty |
| 2 | 509 | 0.74 | 0.82 | 61 | empty |
| 3 | 631 | 0.71 | 0.79 | 47 | empty |
| 4 | 466 | 0.70 | 0.80 | 47 | empty |
| 5 | 454 | 0.63 | 0.77 | 46 | empty |
Compared structures
- 2V26 · Myosin VI (MD) pre-powerstroke state (Mg.ADP.VO4) · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 2V26 · Myosin VI (md) pre-powerstroke state (MG.ADP.VO4) · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 4ANJ · MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 4ANJ · Myosin VI (MDINSERT2-GFP fusion) pre-powerstroke state (MG.ADP.ALF4) · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 2BKI · Myosin VI nucleotide-free (MDinsert2-IQ) crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 2BKI · Myosin VI nucleotide-free (MDINSERT2-iq) crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 3L9I · Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 3L9I · Myosin VI nucleotide-free (MDINSERT2) L310G mutant crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 2BKH · Myosin VI nucleotide-free (MDInsert2) crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 2BKH · Myosin VI nucleotide-free (MDINSERT2) crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 2X51 · M6 delta Insert1 · an experimental structure of the same protein · chain A against A, TM-score 0.50
- 2X51 · M6 delta INSERT1 · an experimental structure of the same protein · chain A against A, TM-score 0.50
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q29122
- Elsewhere: UniProt Q29122 · AlphaFold DB Q29122
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