UniProt Q29122
Unconventional myosin-VI (Q29122)
Unconventional myosin-VI (UniProt Q29122): 18 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q29122
- Protein
- Unconventional myosin-VI
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
19 records of Q29122 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BKH | Myosin VI nucleotide-free (MDInsert2) crystal structure | x-ray diffraction | A | — | — |
| 2BKH | Myosin VI nucleotide-free (MDINSERT2) crystal structure | x-ray diffraction | A | — | — |
| 2BKI | Myosin VI nucleotide-free (MDinsert2-IQ) crystal structure | x-ray diffraction | A | — | — |
| 2BKI | Myosin VI nucleotide-free (MDINSERT2-iq) crystal structure | x-ray diffraction | A | — | — |
| 2V26 | Myosin VI (MD) pre-powerstroke state (Mg.ADP.VO4) | x-ray diffraction | A | — | — |
| 2V26 | Myosin VI (md) pre-powerstroke state (MG.ADP.VO4) | x-ray diffraction | A | — | — |
| 2VAS | Myosin VI (MD-insert2-CaM, Delta-Insert1) Post-rigor state | x-ray diffraction | A | — | — |
| 2VAS | Myosin VI (md-INSERT2-cam, delta-INSERT1) post-rigor state | x-ray diffraction | A | — | — |
| 2VB6 | Myosin VI (MD-insert2-CaM, Delta Insert1) Post-rigor state (crystal form 2) | x-ray diffraction | A | — | — |
| 2VB6 | Myosin VI (md-INSERT2-cam, delta INSERT1) post-rigor state ( crystal form 2) | x-ray diffraction | A | — | — |
| 2X51 | M6 delta Insert1 | x-ray diffraction | A | — | — |
| 2X51 | M6 delta INSERT1 | x-ray diffraction | A | — | — |
| 3GN4 | Myosin lever arm | x-ray diffraction | A, E | — | — |
| 3GN4 | Myosin lever arm | x-ray diffraction | A, E | — | — |
| 3L9I | Myosin VI nucleotide-free (mdinsert2) L310G mutant crystal structure | x-ray diffraction | A | — | — |
| 3L9I | Myosin VI nucleotide-free (MDINSERT2) L310G mutant crystal structure | x-ray diffraction | A | — | — |
| 4ANJ | MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) | x-ray diffraction | A | — | — |
| 4ANJ | Myosin VI (MDINSERT2-GFP fusion) pre-powerstroke state (MG.ADP.ALF4) | x-ray diffraction | A | — | — |
| Q29122 | AlphaFold monomer V2.0 prediction for unconventional myosin-VI (Q29122) | predicted | A | — | 15 (best 0.77) |
Experiment against prediction
- 2V26 chain A against the predicted model Q29122: TM-score 0.94, RMSD 2.51 Å
- 2V26 chain A against the predicted model Q29122: TM-score 0.94, RMSD 2.51 Å
- 4ANJ chain A against the predicted model P42212: TM-score 0.23, RMSD 0.56 Å
- 4ANJ chain A against the predicted model P42212: TM-score 0.23, RMSD 0.56 Å
- 2BKH chain A against the predicted model Q29122: TM-score 0.85, RMSD 3.13 Å
- 2BKH chain A against the predicted model Q29122: TM-score 0.85, RMSD 3.13 Å
- 3L9I chain A against the predicted model Q29122: TM-score 0.85, RMSD 3.17 Å
- 3L9I chain A against the predicted model Q29122: TM-score 0.85, RMSD 3.17 Å
- 2X51 chain A against the predicted model Q29122: TM-score 0.84, RMSD 3.18 Å
- 2X51 chain A against the predicted model Q29122: TM-score 0.84, RMSD 3.18 Å
Elsewhere
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