GL1X · GenesisL1 explorer

MolNFT v1 · #248869 · protein

AlphaFold monomer V2.0 prediction for tetrahydromethanopterin S-methyltransferase subunit a 1 (P80184)

P80184: “AlphaFold monomer V2.0 prediction for tetrahydromethanopterin S-methyltransferase subunit a 1 (P80184)”. 1 pocket (best druggability 0.65). MolNFT v1 #248869 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P80184
Type
protein
Length
238 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x2FCae8136DBc761f6F9310fF638e0F8Ad73E2B9d
Molecule
Tetrahydromethanopterin S-methyltransferase subunit a 1
UniProt
P80184
Pockets
1 · best druggability 0.65

Structure

1 distinct chain · 43% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATetrahydromethanopterin S-methyltransferase subunit a 1protein23843% helix, 11% strandP80184

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11140.650.8922empty

Compared structures

  • 8Q54 · N5-methyl-H4MPT:CoM methyltransferase -coenzyme M complex + CoM · an experimental structure of the same protein · chain A against Q, TM-score 0.20
  • 8Q3V · Cryo-EM structure of the methanogenic Na+ translocating N5-methyl-H4MPT:CoM… · an experimental structure of the same protein · chain A against A, TM-score 0.20

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