MolNFT v1 · #248866 · protein
AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DOB1 (P47047)
P47047: “AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DOB1 (P47047)”. 13 pockets (best druggability 0.81). MolNFT v1 #248866 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P47047
- Type
- protein
- Length
- 1,073 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x68C50954adA417a9303e7cEcfC2b256525160CC6
- Molecule
- ATP-dependent RNA helicase DOB1
- UniProt
- P47047
- Pockets
- 13 · best druggability 0.81
Structure
1 distinct chain · 44% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent RNA helicase DOB1 | protein | 1073 | 44% helix, 15% strand | P47047 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1115 | 0.81 | 0.82 | 102 | empty |
| 2 | 65 | 0.68 | 0.96 | 18 | empty |
| 3 | 341 | 0.66 | 0.80 | 30 | empty |
| 4 | 186 | 0.59 | 0.82 | 30 | empty |
| 5 | 238 | 0.58 | 0.79 | 37 | empty |
Compared structures
- 4U4C · The molecular architecture of the TRAMP complex reveals the organization and interplay of… · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 4U4C · The molecular architecture of the tramp complex reveals the organization and interplay of… · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 2XGJ · Structure of MTR4, a dexh helicase involved in nuclear RNA processing and surveillance · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 2XGJ · Structure of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 5OOQ · Structure of the MTR4 NOP53 complex · an experimental structure of the same protein · chain A against B, TM-score 0.72
- 5OOQ · Structure of the Mtr4 Nop53 Complex · an experimental structure of the same protein · chain A against B, TM-score 0.72
- 4QU4 · Improved refinement of the MTR4 apo crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 4QU4 · Improved refinement of the Mtr4 apo crystal structure · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 6LQS · Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) · an experimental structure of the same protein · chain A against M4, TM-score 0.68
- 6FSZ · Structure of the nuclear RNA exosome · an experimental structure of the same protein · chain A against MM, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P47047
- Elsewhere: UniProt P47047 · AlphaFold DB P47047
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