UniProt P47047
ATP-dependent RNA helicase DOB1 (P47047)
ATP-dependent RNA helicase DOB1 (UniProt P47047), EC 3.6.4.13: 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P47047
- Protein
- ATP-dependent RNA helicase DOB1
- EC
- 3.6.4.13
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 33 · 2 records with a druggable one
Structures
13 records of P47047 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XGJ | Structure of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance | x-ray diffraction | A, B | — | — |
| 2XGJ | Structure of MTR4, a dexh helicase involved in nuclear RNA processing and surveillance | x-ray diffraction | A, B | — | — |
| 4QU4 | Improved refinement of the Mtr4 apo crystal structure | x-ray diffraction | A | — | — |
| 4QU4 | Improved refinement of the MTR4 apo crystal structure | x-ray diffraction | A | — | — |
| 4U4C | The molecular architecture of the TRAMP complex reveals the organization and interplay of its two… | x-ray diffraction | A | — | — |
| 4U4C | The molecular architecture of the tramp complex reveals the organization and interplay of its two… | x-ray diffraction | A | — | — |
| 4WFD | Structure of the Rrp6-Rrp47-Mtr4 interaction | x-ray diffraction | C, F, I | — | — |
| 4WFD | Structure of the RRP6-RRP47-MTR4 interaction | x-ray diffraction | C, F, I | — | — |
| 5OOQ | Structure of the Mtr4 Nop53 Complex | x-ray diffraction | A, B | SO4 | 20 (best 0.75) |
| 5OOQ | Structure of the MTR4 NOP53 complex | x-ray diffraction | A, B | SO4 | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | M4 | — | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | EN | — | — |
| P47047 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DOB1 (P47047) | predicted | A | — | 13 (best 0.81) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 4U4C chain A against the predicted model P47047: TM-score 0.96, RMSD 2.24 Å
- 4U4C chain A against the predicted model P47047: TM-score 0.96, RMSD 2.24 Å
- 2XGJ chain B against the predicted model P47047: TM-score 0.93, RMSD 2.66 Å
- 2XGJ chain B against the predicted model P47047: TM-score 0.93, RMSD 2.66 Å
- 2XGJ chain A against the predicted model P47047: TM-score 0.85, RMSD 4.22 Å
- 2XGJ chain A against the predicted model P47047: TM-score 0.85, RMSD 4.22 Å
- 6LQS chain M4 against the predicted model P47047: TM-score 0.83, RMSD 3.25 Å
- 5OOQ chain B against the predicted model P47047: TM-score 0.81, RMSD 4.89 Å
- 5OOQ chain B against the predicted model P47047: TM-score 0.81, RMSD 4.89 Å
- 5OOQ chain A against the predicted model P47047: TM-score 0.80, RMSD 4.93 Å
Elsewhere
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