AlphaFold monomer V2.0 prediction for tyrosine-protein kinase syk (P43405)

Structure

1 distinct chain.

Compared structures

• 4FL2 · Structural and Biophysical Characterization of the Syk Activation Switch · an experimental structure of the same protein · chain A against A, TM-score 0.86
• 4FL2 · Structural and biophysical characterization of the syk activation switch · an experimental structure of the same protein · chain A against A, TM-score 0.86
• 4FL3 · Structural and biophysical characterization of the syk activation switch · an experimental structure of the same protein · chain A against A, TM-score 0.84
• 4FL3 · Structural and Biophysical Characterization of the Syk Activation Switch · an experimental structure of the same protein · chain A against A, TM-score 0.84
• 4GFG · Crystal structure of spleen tyrosine kinase complexed with R9021 · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 4GFG · Crystal structure of spleen tyrosine kinase complexed with r9021 · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 5CXH · SYK catalytic domain complexed with a potent orally bioavailable thiazole inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 4RX7 · SYK Catalytic Domain Complexed with a Potent Triazine Inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 4WNM · SYK catalytic domain in complex with a potent triazolopyridine inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 4DFN · Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 4DFN · Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 1XBC · Crystal structure of the syk tyrosine kinase domain with Staurosporin · an experimental structure of the same protein · chain A against A, TM-score 0.39

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P43405
• Elsewhere: UniProt P43405 · AlphaFold DB P43405