Research workbench
Structure of MOS1 transposase catalytic domain and raltegravir with mg
Analyse Structure of MOS1 transposase catalytic domain and raltegravir with mg in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4MDB
- Type
- protein
- Length
- 201 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mariner MOS1 transposase
- EC
- 3.1.-.-
- UniProt
- Q7JQ07
- Ligands
- RLT, MG
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mariner MOS1 transposase (EC 3.1.-.-) | protein | 201 | 54% helix, 16% strand | Q7JQ07 |
Ligands and binding sites
- RLT · N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl) carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide · ligand · chains A
- MG · Magnesium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.29 | 0.76 | 14 | empty |
Compared structures
- 4MDB · Structure of Mos1 transposase catalytic domain and Raltegravir with Mg · the same entry in another collection · chain A against A, TM-score 1.00
- Q7JQ07 · AlphaFold monomer V2.0 prediction for mariner MOS1 transposase (Q7JQ07) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7JQ07
- Elsewhere: RCSB PDB 4MDB · PDBe 4MDB · UniProt Q7JQ07
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