Research workbench
Crystal structure of small laccase SSL1 from streptomyces sviceus
Analyse Crystal structure of small laccase SSL1 from streptomyces sviceus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4M3H
- Type
- protein
- Length
- 808 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Copper oxidase
- EC
- 1.10.3.2
- UniProt
- B5HSR1
- Ligands
- CU, O
- Pockets
- 9 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Copper oxidase (EC 1.10.3.2) | protein | 269 | 6% helix, 43% strand | B5HSR1 |
| C | Copper oxidase (EC 1.10.3.2) | protein | 270 | 5% helix, 42% strand | B5HSR1 |
Ligands and binding sites
- CU · Copper (II) ion · metal · 11 copies · chains A, C, B
- O · Oxygen atom · ion · 2 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 334 | 0.84 | 0.94 | 54 | empty |
| 2 | 74 | 0.72 | 0.97 | 21 | empty |
| 3 | 52 | 0.68 | 0.97 | 19 | empty |
| 4 | 154 | 0.53 | 0.80 | 31 | empty |
| 5 | 139 | 0.51 | 0.80 | 31 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1889 Ų buried · 37 hydrogen bonds · protein-protein
- B–C · 1810 Ų buried · 36 hydrogen bonds · protein-protein
- A–B · 1806 Ų buried · 33 hydrogen bonds · protein-protein
Compared structures
- 4M3H · Crystal structure of small laccase Ssl1 from Streptomyces sviceus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B5HSR1
- Elsewhere: RCSB PDB 4M3H · PDBe 4M3H · UniProt B5HSR1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.