Research workbench
Crystal structure of human phosphoglucose ISOMERASE/NEUROLEUKIN/AUTOCRINE motility FACTOR/MATURATION factor
Analyse Crystal structure of human phosphoglucose ISOMERASE/NEUROLEUKIN/AUTOCRINE… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IAT
- Type
- protein
- Length
- 556 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoglucose isomerase
- EC
- 5.3.1.9
- UniProt
- P06744
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoglucose isomerase (EC 5.3.1.9) | protein | 556 | 56% helix, 13% strand | P06744 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 268 | 0.59 | 0.79 | 38 | SO4, BME |
| 2 | 70 | 0.49 | 0.84 | 16 | empty |
| 3 | 127 | 0.44 | 0.77 | 17 | empty |
Compared structures
- 1IAT · Crystal structure of human phosphoglucose ISOMERASE/NEUROLEUKIN/AUTOCRINE motility… · the same entry in another collection · chain A against A, TM-score 1.00
- P06744 · AlphaFold monomer V2.0 prediction for glucose-6-phosphate isomerase (P06744) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06744
- Elsewhere: RCSB PDB 1IAT · PDBe 1IAT · UniProt P06744
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