UniProt P06744
Glucose-6-phosphate isomerase (P06744)
Glucose-6-phosphate isomerase (UniProt P06744), EC 5.3.1.9: 15 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P06744
- Protein
- Glucose-6-phosphate isomerase
- EC
- 5.3.1.9
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 21 · 2 records with a druggable one
Structures
16 records of P06744 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IAT | Crystal structure of human phosphoglucose ISOMERASE/NEUROLEUKIN/AUTOCRINE motility… | x-ray diffraction | A | — | — |
| 1IAT | Crystal structure of human phosphoglucose ISOMERASE/NEUROLEUKIN/AUTOCRINE motility… | x-ray diffraction | A | — | — |
| 1IRI | Crystal structure of human autocrine motility factor complexed with an inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 1IRI | Crystal structure of human autocrine motility factor complexed with an inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 1JIQ | Crystal Structure of Human Autocrine Motility Factor | x-ray diffraction | A, B, C, D | — | — |
| 1JIQ | Crystal structure of human autocrine motility factor | x-ray diffraction | A, B, C, D | — | — |
| 1JLH | Human Glucose-6-phosphate Isomerase | x-ray diffraction | A, B, C, D | — | — |
| 1JLH | Human glucose-6-phosphate isomerase | x-ray diffraction | A, B, C, D | — | — |
| 1NUH | The crystal structure of human phosphoglucose isomerase complexed with 5-phosphoarabinonate | x-ray diffraction | A | — | — |
| 1NUH | The crystal structure of human phosphoglucose isomerase complexed with 5-phosphoarabinonate | x-ray diffraction | A | — | — |
| 6XUH | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | x-ray diffraction | A, B, C, D | PA5, O1B | — |
| 6XUI | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | x-ray diffraction | A, B, C, D | PA5 | 20 (best 0.85) |
| 6XUI | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | x-ray diffraction | A, B, C, D | PA5 | — |
| 8BBH | The crystal structure of a mouse Fab fragment TL1 in complex with a human Glucose-6-phosphate… | x-ray diffraction | A | — | — |
| 8P2K | Ternary complex of translating ribosome, NAC and METAP1 | electron microscopy | BK | UNX | 1 (best 0.88) |
| P06744 | AlphaFold monomer V2.0 prediction for glucose-6-phosphate isomerase (P06744) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1JLH chain B against the predicted model P06744: TM-score 1.00, RMSD 0.44 Å
- 1JLH chain B against the predicted model P06744: TM-score 1.00, RMSD 0.44 Å
- 1JLH chain D against the predicted model P06744: TM-score 1.00, RMSD 0.45 Å
- 1JLH chain D against the predicted model P06744: TM-score 1.00, RMSD 0.45 Å
- 1JIQ chain B against the predicted model P06744: TM-score 1.00, RMSD 0.45 Å
- 1JIQ chain B against the predicted model P06744: TM-score 1.00, RMSD 0.45 Å
- 1JLH chain C against the predicted model P06744: TM-score 1.00, RMSD 0.46 Å
- 1JLH chain C against the predicted model P06744: TM-score 1.00, RMSD 0.46 Å
- 1JIQ chain D against the predicted model P06744: TM-score 1.00, RMSD 0.47 Å
- 1JIQ chain D against the predicted model P06744: TM-score 1.00, RMSD 0.47 Å
Elsewhere
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