Research workbench
Kinase domain mutant of human itk in complex with a covalently-binding inhibitor
Analyse Kinase domain mutant of human itk in complex with a covalently-binding inhibitor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4KIO
- Type
- protein
- Length
- 972 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q08881
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 240 | — | Q08881 |
| B | — | protein | 239 | — | Q08881 |
| C | — | protein | 251 | — | Q08881 |
| D | — | protein | 242 | — | Q08881 |
Compared structures
- 4KIO · Kinase domain mutant of human Itk in complex with a covalently-binding inhibitor · the same entry in another collection · chain D against D, TM-score 1.00
- Q08881 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase ITK/TSK (Q08881) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08881
- Elsewhere: RCSB PDB 4KIO · PDBe 4KIO · UniProt Q08881
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